Coursey B M
Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.
Thyroid. 1997 Apr;7(2):285-8. doi: 10.1089/thy.1997.7.285.
The National Institute of Standards and Technology, NIST (formerly National Bureau of Standards), is the nation's standards laboratory for civilian technology. NIST develops and maintains the nation's physical measurement standards for medical therapy and diagnostics. For the past 50 years, NIST has developed radioactivity Standard Reference Materials (SRMs) for radioiodines as well as decay-scheme data and test methods for use by the radiopharmaceutical manufacturers in their quality assurance and quality control at the point of manufacture. Methods of standardizing radioiodines include 4 pi beta-gamma coincidence counting (131I), 4 pi beta-gamma anti-coincidence counting (129I), 4 pi(e,x)-gamma coincidence counting (123I), and x-gamma sum peak coincidence counting (125I). NIST also uses sources standardized by these techniques to calibrate re-entrant ionization chambers (dose calibrators) and scintillation counters. SRMs of 131I and 125I are now available on an annual basis, and the long-lived 129I has recently been reissued.
美国国家标准与技术研究院（NIST，前身为国家标准局）是美国民用技术的标准实验室。NIST制定并维护用于医学治疗和诊断的国家物理测量标准。在过去50年里，NIST开发了用于放射性碘的放射性标准参考物质（SRM）以及衰变方案数据和测试方法，供放射性药物制造商在生产过程中的质量保证和质量控制使用。标准化放射性碘的方法包括4πβ-γ符合计数（用于131I）、4πβ-γ反符合计数（用于129I）、4π(e,x)-γ符合计数（用于123I）以及x-γ和峰符合计数（用于125I）。NIST还使用通过这些技术标准化的源来校准重入式电离室（剂量校准器）和闪烁计数器。131I和125I的SRM现在每年都有供应，并且长寿命的129I最近已重新发布。
