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半侧鼻发育不全:一例病例报告及过去25年文献综述

Heminasal aplasia: a case report and review of the literature of the last 25 years.

作者信息

van Kempen A A, Nabben F A, Hamel B C

机构信息

Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands.

出版信息

Clin Dysmorphol. 1997 Apr;6(2):147-52.

PMID:9134295
Abstract

We report a child with right-sided heminasal aplasia in combination with anomalies of the right eye and maxilla. Unilateral aplasia of the nose is a rare congenital malformation. It is often associated with other malformations of the facial region, including abnormalities of the eye and lacrimal system, proboscis lateralis, and facial bone malformations. The eye anomalies in our patient consisted of microphthalmia with blepharophimosis and coloboma of the iris, retina and upper eyelid. Also hypoplasia of the lacrimal apparatus and right maxilla, and a rudimentary alveolar cleft on the same side were present. The embryological development of the midface can explain this association of anomalies.

摘要

我们报告了一名患有右侧半侧鼻发育不全并伴有右眼和上颌骨异常的儿童。单侧鼻发育不全是一种罕见的先天性畸形。它常与面部其他畸形相关,包括眼和泪系统异常、侧鼻鼻管、以及面部骨骼畸形。我们患者的眼部异常包括小眼症伴睑裂狭小以及虹膜、视网膜和上睑裂孔。同时还存在泪器和右上颌骨发育不全,以及同侧的牙槽嵴裂。面中部的胚胎发育可以解释这种异常的关联。

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