Au Y K, Collins W P, Patel J S, Asamoah A
Department of Ophthalmology, Louisiana State University Medical School- Shreveport 71130-3932, USA.
Ophthalmic Genet. 1997 Mar;18(1):39-41. doi: 10.3109/13816819709057882.
PURPOSE/METHODS: A variety of ocular and periocular manifestations have been described in Noonan syndrome. Collagen abnormalities have been described; however, to our knowledge spontaneous corneal rupture has not been reported. A forty-three-year-old female who presented with spontaneous corneal rupture was later diagnosed as having Noonan syndrome.
RESULTS/CONCLUSIONS: Collagen abnormalities have been described with Noonan syndrome and this is likely the cause of corneal rupture in this patient.
目的/方法：努南综合征有多种眼部及眼周表现。已有胶原异常的相关描述；然而，据我们所知，自发性角膜破裂尚未见报道。一名43岁女性因自发性角膜破裂就诊，后来被诊断为努南综合征。
结果/结论：努南综合征存在胶原异常，这可能是该患者角膜破裂的原因。
