Phillips A, Campbell M
Wyeth Research, Berkshire, UK.
J Biopharm Stat. 1997 May;7(2):215-26. doi: 10.1080/10543409708835182.
The basis of sample size calculations is usually needed in protocols for clinical trials and when publishing results in respected journals. Although a large amount of research has been undertaken on sample size estimation for different trial designs, in practice the methods are rarely used. This paper describes some useful theory that has practical relevance.
在临床试验方案以及向知名期刊发表研究结果时，通常都需要样本量计算的依据。尽管针对不同试验设计的样本量估计已开展了大量研究，但在实际中这些方法很少被使用。本文介绍了一些具有实际相关性的有用理论。
