Kaneda M, Kuroda K, Fujita M, Shinkai H
Department of Dermatology, School of Medicine, Chiba University, Japan.
Clin Exp Dermatol. 1996 Sep;21(5):360-4.
We obtained a successful response to PUVA therapy in a 51-year-old Japanese man who had multiple nodules of the trunk, extremities and scalp along with polyclonal hypergammaglobulinaemia; the scalp lesions were associated with extensive alopecia. Examination of skin biopsies showed a dense infiltrate of mature plasma cells in the dermis and hair follicles; no systemic disease or functional involvement of other organs was detected. The clinical and histological findings were compatible with cutaneous plasmacytosis and treatment with topical PUVA gradually reduced the size and number of the lesions.
我们对一名51岁的日本男性成功实施了补骨脂素紫外线A光化学疗法（PUVA疗法）。该患者躯干、四肢及头皮出现多个结节，并伴有多克隆性高球蛋白血症；头皮损害伴有广泛脱发。皮肤活检显示真皮和毛囊中有密集的成熟浆细胞浸润；未检测到系统性疾病或其他器官的功能受累。临床和组织学表现符合皮肤浆细胞增多症，外用PUVA治疗逐渐减小了皮损的大小并减少了其数量。
