Martín J M, Calduch L, Monteagudo C, Molina I, Ramón D, Alonso V, Jordá E
Department of Dermatology, Hospital Clínico Universitario, Valencia, Spain.
J Eur Acad Dermatol Venereol. 2006 Apr;20(4):428-31. doi: 10.1111/j.1468-3083.2006.01433.x.
Cutaneous plasmacytosis is a rare disorder characterized by a benign proliferation of mature plasma cells that appears as multiple dark-brown to purplish skin lesions, often associated with polyclonal hypergammaglobulinaemia. We present the case of a 55-year-old Caucasian man who suffered from a cutaneous plasmacytosis associated with two different carcinomas. Cutaneous plasmacytosis seems to be a reactive process because most cases reported are not associated with any apparent underlying disease. Nevertheless, because few reported cases were associated with malignancies, screening of additional neoplasms would be justified.
皮肤浆细胞增多症是一种罕见的疾病，其特征为成熟浆细胞的良性增殖，表现为多个深棕色至紫色的皮肤损害，常伴有多克隆高球蛋白血症。我们报告一例55岁的白种男性患者，其患有与两种不同癌症相关的皮肤浆细胞增多症。皮肤浆细胞增多症似乎是一种反应性过程，因为大多数报道的病例与任何明显的潜在疾病无关。然而，由于少数报道的病例与恶性肿瘤相关，因此对其他肿瘤进行筛查是合理的。
