Merlín M, Gándara S, Iannicillo H, Dutack A, Raffo L, Di Bartolomeo S, Di Bella A, Pelluffo G, Varsky C
Hospital Nacional Prof. A. Posadas Prov. Buenos Aires, Argentina.
Acta Gastroenterol Latinoam. 1996;26(1):15-22.
Assessment of the rate of Diarrhoea in an infected HIV population of our medium. Assessment of its etiology, risk factors and response to treatment in both presentation of disease (Acute and chronic).
This is a retrospective analysis of HIV and/or AIDS patients and diarrhea. The analytic points were: the clinical pattern of diarrhea (acute or chronic), risk factors, age, sex, etiology, stage of the disease, and response rate to treatment.
Hospital Prof. A. Posadas, that is situated in the greater Buenos Aires, and that functions as a referral centre for AIDS patients.
435 case records that were followed up through June 1987/ March 1994 were reviewed; 109 of the total number suffered from diarrhea.
The rate of diarrhoea in the studied population was 25% (109/435). This represented the first symptom of HIV infection in 18.3% of the patients (20/109), 49% had acute diarrhea and 51% had chronic diarrhea. An etiologic agent was established in 52.3% of the chronic diarrhoeas and in the 17.7% of the acute ones, with a 35.4% of a global isolation when basic stool test were made. Sixty three percent of the patients with chronic diarrhoea were in stage IV of HIV infection. The 78.3% of the acute diarrhoeas and 46% of the chronic ones were responsive to specific or symptomatic treatment.
HIV antibodies determinations should be included in the study protocol of diarrhea, especially in young patients. Chronic diarrhea could be related to final stages of the disease, with lower response to treatment. Endoscopy studies should be useful when the stool tests are negative, specially in the Cytomegalovirus (CMV) and Mycobacterium complex avium intracellulare (MAI) search.
评估我市感染艾滋病毒人群中的腹泻发生率。评估其病因、危险因素以及在疾病的两种表现形式（急性和慢性）下对治疗的反应。
这是一项对艾滋病毒和/或艾滋病患者及腹泻情况的回顾性分析。分析要点包括：腹泻的临床模式（急性或慢性）、危险因素、年龄、性别、病因、疾病阶段以及治疗反应率。
位于大布宜诺斯艾利斯的A. 波萨达斯教授医院，该医院是艾滋病患者的转诊中心。
回顾了截至1987年6月/1994年3月随访的435份病例记录；其中109人患有腹泻。
研究人群中的腹泻发生率为25%（109/435）。这在18.3%的患者（20/109）中是艾滋病毒感染的首发症状，49%的患者为急性腹泻，51%为慢性腹泻。在52.3%的慢性腹泻病例和17.7%的急性腹泻病例中确定了病原体，进行基本粪便检测时总体分离率为35.4%。63%的慢性腹泻患者处于艾滋病毒感染的IV期。78.3%的急性腹泻和46%的慢性腹泻对特异性或对症治疗有反应。
腹泻研究方案中应包括艾滋病毒抗体检测，尤其是在年轻患者中。慢性腹泻可能与疾病的终末期有关，对治疗的反应较低。当粪便检测为阴性时，内镜检查可能有用，特别是在寻找巨细胞病毒（CMV）和鸟分枝杆菌复合体（MAI）时。
