Danazol treatment and follow-up of patients with endometriosis.

In conclusion, we find that danazol has proved to be highly effective as a treatment for endometriosis. On the dosage used, we have not achieved the freedom from side-effects which we had hoped for, but in general these have been much less severe than those with combined oestrogen progestogen preparations. We propose continuing the trial with a reduced dosage of 400 mg daily in the hope of further reducing the incidence of side-effects.