Siegfried J
Neurochirurgie, Klinik im Park, Zürich.
Ther Umsch. 1997 Feb;54(2):83-6.
The hallmark of trigeminal neuralgia is the abrupt onset of short pains in the face or in a part of the face, described as stabbing, lightning or electric shocks. Attacks are often triggered by cutaneous stimuli to the face or the oral cavity, which may be such minor activities as talking, chewing, brushing the teeth, or even wind blowing on the face. As a result, facial hygiene as well as a good diet may be neglected. Although 1% of the patients may eventually develop the disorder bilaterally, pain does not cross the midline during any single episode. The clinical course is characterized by exacerbations and remissions, but as the disorder progresses, remissions become shorter and exacerbations more severe. Carbamazepine is the most powerful drug for this condition, but side effects may occur. Neurosurgical treatment may then be considered; the different techniques and approaches are mentioned. Other pain conditions in the face will be reviewed. If the trigeminal neuralgia may be considered as a nerve irritation, like the glossopharyngeal neuralgia and the nasociliary neuralgia, nerve lesion may elicit neurogenic or neuropathic pain, characterized by chronic burning pain; post-zoster pain, iatrogenic and posttraumatic pain illustrate this condition. Cluster headache (Horton neuralgia), Sluder's neuralgia and auriculotemporal neuralgia may be related to a dysfunction of the autonomous nervous system. Finally, lesion in the mandibular joint may cause unilateral facial pain.
三叉神经痛的特点是面部或面部某一部位突然出现短暂疼痛,描述为刺痛、闪电样或电击样。发作常由面部或口腔的皮肤刺激引发,这些刺激可能是诸如说话、咀嚼、刷牙等轻微活动,甚至是风吹在脸上。因此,面部卫生以及良好的饮食可能会被忽视。虽然1%的患者最终可能双侧发病,但在任何单次发作中疼痛都不会越过中线。临床病程的特点是发作与缓解交替,但随着病情进展,缓解期会变短,发作会更严重。卡马西平是治疗这种疾病最有效的药物,但可能会出现副作用。此时可考虑神经外科治疗;文中提到了不同的技术和方法。还将回顾面部的其他疼痛情况。如果三叉神经痛可被视为一种神经刺激,如舌咽神经痛和鼻睫状神经痛,神经损伤可能引发神经源性或神经性疼痛,其特点是慢性灼痛;带状疱疹后疼痛、医源性疼痛和创伤后疼痛说明了这种情况。丛集性头痛(霍顿神经痛)、斯路德神经痛和耳颞神经痛可能与自主神经系统功能障碍有关。最后,下颌关节病变可能导致单侧面部疼痛。