Ortega-Carnicer J, Alcázar R, De la Torre M, Benezet J
Intensive Care Unit, Hospital Alarcos, Ciudad Real, Spain.
J Electrocardiol. 1997 Apr;30(2):143-5. doi: 10.1016/s0022-0736(97)80023-4.
Unexplained sudden deaths following use of pentavalent antimonial drugs have been described, presumably owing to ventricular arrhythmias. A patient is reported with QT interval prolongation and syncopal episodes related to torsade de pointes following treatment of visceral leishmaniasis with meglumine antimoniate. This is the first reported case of documented torsade de pointes following treatment with pentavalent antimonial drugs.