Metabolism of labeled fatty ozonides administrated intravenously in rats.

The distribution and metabolism of uniformly labeled fatty ozonides administrated intravenously in rats were studied. More than 90% of radioactivity was recovered in the lung tissue even 4 to 8 hr after injection of labeled ozonides, and approximately 60% of total radioactivity incorporated into the lung tissue remained as fatty ozonides. A slight amount of radioactivity, which was mainly incorporated into phospholipid and triglyceride, was recovered in liver and kidney.