Ukai K, Fuji A, Nishiwaki J, Yamada T, Hotta N, Kobayashi Y, Kondo C, Miyajima K, Takada T, Kinoshita Y, Hanai S
Department of Medicine, Holy Spirit Hospital, Nagoya.
Intern Med. 1997 Mar;36(3):186-90. doi: 10.2169/internalmedicine.36.186.
We report a case of giant hepatic angiomyolipoma in a 68-year-old woman who had an increase in the fibrinolytic activity concomitant with disseminated intravascular coagulation (DIC). The presence of the tumor was confirmed by ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen and the selective arteriography of the liver via the superior mesenteric artery. Following treatment with heparin and gabexate mesilate, abnormal hemostatic values were corrected. Furthermore, the surgical removal of the huge hepatic angiomyolipoma completely normalized the alternations of the clotting system. These findings suggest that giant hepatic angiomyolipoma was profoundly associated with DIC.
我们报告了一例68岁女性的巨大肝脏血管平滑肌脂肪瘤病例，该患者在发生弥散性血管内凝血（DIC）时纤溶活性增加。通过腹部超声（US）、计算机断层扫描（CT）、磁共振成像（MRI）以及经肠系膜上动脉的肝脏选择性动脉造影术确诊了肿瘤的存在。在使用肝素和甲磺酸加贝酯治疗后，异常的止血值得到了纠正。此外，手术切除巨大的肝脏血管平滑肌脂肪瘤使凝血系统的改变完全恢复正常。这些发现表明，巨大肝脏血管平滑肌脂肪瘤与DIC密切相关。
