Shimohigashi Y, Lee S, Aoyagi H, Kato T, Izumiya N
Int J Pept Protein Res. 1977;10(3):197-205.
An AM-toxin analog, cyclotetradepsipeptide, containing an O-methyl-L-tyrosine residue in place of an L-2-amino-5-arylpentanoic acid residue in AM-toxins has been prepared by a conventional method. The synthesis was attempted through six different routes and the desired analog was obtained by one such procedure. This compound showed extremely weak activity in causing necrosis on apple leaves.
一种AM毒素类似物，环四缩酚酸肽，已通过常规方法制备，其中AM毒素中的L-2-氨基-5-芳基戊酸残基被O-甲基-L-酪氨酸残基取代。尝试了六种不同的路线进行合成，通过其中一种方法得到了所需的类似物。该化合物在引起苹果叶片坏死方面表现出极其微弱的活性。
