de Rooij M J, Rampen F H, Schouten L J, Neumann H A
Department of Dermatology, University Hospital Nijmegen, The Netherlands.
Dermatol Surg. 1997 Mar;23(3):197-201.
Follow-up information on free melanoma screening clinics is not readily available.
We studied the follow-up, compliance, and outcome of positive screenees after a screening campaign for melanoma in the Netherlands.
Of the 4146 participants, 486 (11.7%) had a suspicious premalignant or malignant lesion warranting referral to his or her general physician indicating the proposed line of management. Participants with borderline lesions were not referred. Referral of borderline cases should have resulted in a considerable increase of the number of positive screenees (18.1%). All positive screenees but two gave permission for follow-up. Only 18 screenees (3.7%) were lost during follow-up. Moreover, one screenee with a presumed basal cell carcinoma and six screenees suspicious of having a premalignant lesion decided not to seek medical attention despite several reminders. The positive predictive value for melanoma was 17.2%, and for nonmelanoma skin cancers was 42.9%.
A selective referral policy may reduce the generated costs of melanoma screenings substantially. Adequate follow-up of positive screenees is mandatory in order to determine the ultimate yield and usefulness of such campaigns.
关于免费黑色素瘤筛查诊所的随访信息不易获取。
我们研究了荷兰黑色素瘤筛查活动后阳性筛查对象的随访情况、依从性和结局。
在4146名参与者中,486名(11.7%)有可疑的癌前或恶性病变,需转诊至其全科医生处,并指明建议的治疗方案。临界病变的参与者未被转诊。转诊临界病例本应使阳性筛查对象的数量大幅增加(18.1%)。除两名外,所有阳性筛查对象均同意随访。随访期间仅18名筛查对象(3.7%)失访。此外,一名疑似基底细胞癌的筛查对象和六名疑似有癌前病变的筛查对象尽管多次收到提醒,仍决定不寻求医疗关注。黑色素瘤的阳性预测值为17.2%,非黑色素瘤皮肤癌的阳性预测值为42.9%。
选择性转诊政策可能会大幅降低黑色素瘤筛查产生的成本。为了确定此类筛查活动的最终收益和实用性,对阳性筛查对象进行充分随访是必不可少的。