Alagiri M, Chottiner S, Ratner V, Slade D, Hanno P M
Department of Urology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
Urology. 1997 May;49(5A Suppl):52-7. doi: 10.1016/s0090-4295(99)80332-x.
To determine the prevalence of concomitant disease in individuals with interstitial cystitis and to compare these results to the general population.
We used a questionnaire-based study evaluating 12 disease processes and a survey of interstitial cystitis characteristics. The population was 2,405 individuals with interstitial cystitis who responded to the initial survey and an additional 277 individuals who were randomly selected and individually contacted.
Allergies, irritable bowel syndrome, and sensitive skin were the most common diseases in the interstitial cystitis population. In comparison to the general population, individuals with interstitial cystitis are 100 times more likely to have inflammatory bowel disease and 30 times more likely to have systemic lupus erythematosus. In addition, allergies, irritable bowel syndrome, sensitive skin, and fibromyalgia have an increased association with interstitial cystitis.
Interstitial cystitis has, as yet, an unexplained association with certain other chronic disease and pain syndromes.
确定间质性膀胱炎患者中伴发疾病的患病率,并将这些结果与普通人群进行比较。
我们采用了一项基于问卷的研究,评估12种疾病进程,并对间质性膀胱炎的特征进行调查。研究人群包括2405名对初始调查做出回应的间质性膀胱炎患者,以及另外277名随机选择并单独联系的患者。
过敏、肠易激综合征和敏感皮肤是间质性膀胱炎患者中最常见的疾病。与普通人群相比,间质性膀胱炎患者患炎症性肠病的可能性高100倍,患系统性红斑狼疮的可能性高30倍。此外,过敏、肠易激综合征、敏感皮肤和纤维肌痛与间质性膀胱炎的关联增加。
间质性膀胱炎与某些其他慢性疾病和疼痛综合征之间存在尚未明确解释的关联。