Kojima M, Naya Y, Inoue W, Ukimura O, Watanabe M, Saitoh M, Watanabe H
Department of Urology, Kyoto Prefectural University of Medicine, Japan.
J Urol. 1997 Jun;157(6):2160-5.
Our study was conducted to reveal quantitatively the relative effects of age and ultrasonic appearance of benign prostatic hyperplasia (BPH) on urinary symptoms as evaluated by the American Urological Association (AUA) symptom index score.
In 929 examinees (732 with a normal prostate and 197 with BPH) on a mass screening program for prostatic diseases using transrectal ultrasonography in Japan, the AUA symptom score was compared to age, prostatic volume and presumed circle area ratio using simple and multiple regression analyses.
Simple regression analysis demonstrated the symptom score to correlate significantly with age (R = 0.162, p < 0.0001), prostatic volume (R = 0.072, p = 0.0281) and presumed circle area ratio (R = 0.150, p < 0.0001). However, multiple regression analysis demonstrated that age and presumed circle area ratio were significant independent determinants of the total symptom score. Among 7 symptoms included in the AUA symptom index weak stream and hesitancy scores were not influenced by age, prostatic volume or presumed circle area ratio.
As a parameter representing the degree of BPH in terms of the severity of urinary symptoms, presumed circle area ratio was preferable to prostatic volume. Regression analyses confirmed again that the AUA symptom index was influenced considerably by age and was not specific to BPH.
本研究旨在通过美国泌尿外科学会（AUA）症状指数评分，定量揭示年龄和良性前列腺增生（BPH）的超声表现对尿路症状的相对影响。
在日本一项使用经直肠超声对前列腺疾病进行大规模筛查的项目中，对929名受检者（732名前列腺正常者和197名BPH患者）进行研究，通过简单和多元回归分析将AUA症状评分与年龄、前列腺体积和假定的圆形面积比进行比较。
简单回归分析显示症状评分与年龄（R = 0.162，p < 0.0001）、前列腺体积（R = 0.072，p = 0.0281）和假定的圆形面积比（R = 0.150，p < 0.0001）显著相关。然而，多元回归分析表明年龄和假定的圆形面积比是总症状评分的显著独立决定因素。在AUA症状指数所包含的7种症状中，尿流缓慢和排尿犹豫评分不受年龄、前列腺体积或假定的圆形面积比的影响。
作为从尿路症状严重程度方面代表BPH程度的参数，假定的圆形面积比优于前列腺体积。回归分析再次证实AUA症状指数受年龄影响较大，并非BPH所特有。
