Taneike R, Kojima M, Saitoh M
Department of Nursing for Adults, College of Medical Technology, Kyoto Prefectural University of Medicine.
Tohoku J Exp Med. 1997 Oct;183(2):135-50. doi: 10.1620/tjem.183.135.
The aim of the present study is to correlate transrectal ultrasonic planimetric parameters of the prostate in relation to age and urinary symptoms as evaluated by the American Urological Association (AUA) symptom index score for benign prostatic hyperplasia (BPH). In 647 examinees on a mass screening program for prostatic diseases using transrectal sonography (TRS) in Japan, prostatic volume, transition zone volume, transition zone index (transition zone volume/prostatic volume) and presumed circle area ratio (PCAR) were determined using transrectal ultrasonic planimetry and compared with age and AUA symptom score. Increase in age, prostatic volume, transition zone volume and PCAR were significantly correlated with AUA symptom score. However, multiple regression analysis demonstrated that age and PCAR were the only significant independent determinant of symptom score. In particular, PCAR was the only significant determinants of symptom score in men with an intermediately enlarged prostate (20-30 ml in volume). The most significant difference in AUA symptom score was found between subgroups divided by PCAR with a cutoff point of 0.8. Among the planimetric parameters obtained by TRS, PCAR was the most powerful for evaluating BPH in terms of the severity of lower urinary tract symptoms.
本研究的目的是将前列腺经直肠超声平面测量参数与年龄以及通过美国泌尿外科学会（AUA）良性前列腺增生（BPH）症状指数评分评估的泌尿症状相关联。在日本一项使用经直肠超声检查（TRS）进行前列腺疾病大规模筛查的项目中，对647名受检者进行了研究，采用经直肠超声平面测量法测定前列腺体积、移行区体积、移行区指数（移行区体积/前列腺体积）和假定圆面积比（PCAR），并将其与年龄和AUA症状评分进行比较。年龄、前列腺体积、移行区体积和PCAR的增加与AUA症状评分显著相关。然而多元回归分析表明，年龄和PCAR是症状评分仅有的显著独立决定因素。特别是，PCAR是前列腺中度增大（体积为20 - 30 ml）男性症状评分的唯一显著决定因素。在以0.8为分界点按PCAR划分的亚组之间，AUA症状评分差异最为显著。在通过TRS获得的平面测量参数中，就下尿路症状的严重程度而言，PCAR在评估BPH方面最为有效。
