Tjensvoll A B, Gilhus N E
Nevrologisk avdeling, Haukeland Sykehus, Bergen.
Tidsskr Nor Laegeforen. 1997 Feb 10;117(4):510-3.
Over a four-year period, all in-patients at our department with the diagnosis of polio-sequelae were clinically examined for development of new neuromuscular deficit. 19 out of 125 patients (15%) had developed a postpolio syndrome. All 19 had acquired additional functional deficit and 17 new, localized pareses. Five patients had developed polio-related hypoventilation. The mean time from acute poliomyelitis to debut of the post-polio syndrome was 39 years. The post-polio syndrome occurred in patients with severe pareses in the acute stage, but was not related to age, sex or specific epidemic. Most of the 106 other patients had similar subjective complaints but did not have any clinical signs indicating new neuromuscular deficit. 67 of these patients had tendinitis and/or myalgia and 83 had chronic pain. Whereas many patients have progressive symptoms many years after poliomyelitis, only a minority develop the post-polio syndrome.
在四年期间，对我们科室所有诊断为小儿麻痹后遗症的住院患者进行了临床检查，以确定是否出现新的神经肌肉功能缺陷。125名患者中有19名（15%）出现了小儿麻痹后遗症综合征。所有19名患者都出现了额外的功能缺陷和17处新的局部麻痹。5名患者出现了与小儿麻痹相关的通气不足。从急性脊髓灰质炎到小儿麻痹后遗症综合征首次出现的平均时间为39年。小儿麻痹后遗症综合征发生在急性期有严重麻痹的患者中，但与年龄、性别或特定疫情无关。其他106名患者中的大多数有类似的主观症状，但没有任何临床体征表明有新的神经肌肉功能缺陷。其中67名患者有肌腱炎和/或肌痛，83名患者有慢性疼痛。虽然许多患者在脊髓灰质炎多年后有进行性症状，但只有少数人会发展为小儿麻痹后遗症综合征。
