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[大鼠甲状腺次全切除、内照射或外照射后血液中甲状腺激素浓度的变化动态]

[Dynamics of changes in the concentration of thyroid hormones in in rat blood after subtotal thyroidectomy, internal, or external irradiation].

作者信息

Shkumatov L M, Krylova I M, Markova A G, Bagel' I M

出版信息

Vopr Med Khim. 1996 Apr-Jun;42(2):111-4.

PMID:9148592
Abstract

Thyroidectomy or administration of high activities (> 1.1 Mbq) of 131I to rats causes initial decrease in blood concentration of thyroid hormones which returns to the normal level. Administration of lower doses (< 1.1 Mbq) of radioactive iodine or external radiation (1, 3, 6 Gr) did not cause similar changes. Data obtained that: 1) thyroid gland is relatively radioresistant organ with high reparative function after surgical or radioactive damage; 2) alterations of thyroid status after the external radiation are not related to a direct action of radiation on the thyroid gland.

摘要

对大鼠进行甲状腺切除术或给予高活度(>1.1 兆贝可)的 131I 会导致甲状腺激素血浓度最初下降,随后恢复到正常水平。给予较低剂量(<1.1 兆贝可)的放射性碘或外部辐射(1、3、6 戈瑞)不会引起类似变化。获得的数据表明:1)甲状腺是相对抗辐射的器官,在手术或放射性损伤后具有较高的修复功能;2)外部辐射后甲状腺状态的改变与辐射对甲状腺的直接作用无关。

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