Claeys L G
Department of Vascular Surgery, General Hospital Cologne-Porz, Cologne Medical School, University of Cologne, Germany.
Artif Organs. 1997 Mar;21(3):201-6. doi: 10.1111/j.1525-1594.1997.tb04653.x.
Epidural spinal cord stimulation (ESCS) has been suggested as a method to improve microcirculatory blood flow and to reduce the amputation rate in vascular patients. We studied the effects of ESCS on microcirculatory blood flow in 237 patients with nonreconstructible peripheral arterial occlusive disease. Clinical status was classified as Fontaine Stage 3 (ischemic rest pain) in 169 patients and as Fontaine Stage 4 (ulcers/gangrene) in 68 patients. After a mean follow-up period of 31.2 months, major pain relief (> 75%) was noticed in patients who retained their limbs. Sixty-four patients underwent major amputation despite ESCS. Clinical improvement was confirmed by the increase in transcutaneous oxygen (TcPO2).
硬膜外脊髓刺激（ESCS）已被提议作为一种改善微血管血流并降低血管疾病患者截肢率的方法。我们研究了ESCS对237例不可重建的外周动脉闭塞性疾病患者微血管血流的影响。临床状态分为169例Fontaine 3期（缺血性静息痛）和68例Fontaine 4期（溃疡/坏疽）患者。平均随访31.2个月后，保留肢体的患者出现了明显的疼痛缓解（>75%）。尽管进行了ESCS，仍有64例患者接受了大截肢手术。经皮氧分压（TcPO2）升高证实了临床改善。
