Avgerinos A, Skliros P, Pyrovolakis J, Stathakos D
J Clin Pathol. 1977 Sep;30(9):857-61. doi: 10.1136/jcp.30.9.857.
In a study of the lipoprotein pattern in multiple myelomatosis electrophoresis on agarose gel showed abnormal lipoproteins, named paralipoproteins (p-Lp), in 24 out of 30 normolipidaemic patients. These paralipoproteins were grouped according to their mobility into one or another of the following types: (1) p-Lp1 with a mobility identical with that of gamma-globulin, (2) p-Lp2 with a mobility between that of beta- and gamma-globulin, (3) p-Lp3 with a mobility identical with that of beta-globulin. On ultracentrifugation the abnormal lipoproteins were found to have a density above 1-063 g/ml.
在一项关于多发性骨髓瘤脂蛋白模式的研究中,对30名血脂正常的患者进行琼脂糖凝胶电泳,结果显示其中24名患者存在异常脂蛋白,称为副脂蛋白(p-Lp)。这些副脂蛋白根据其迁移率被分为以下一种或另一种类型:(1)p-Lp1,迁移率与γ-球蛋白相同;(2)p-Lp2,迁移率介于β-球蛋白和γ-球蛋白之间;(3)p-Lp3,迁移率与β-球蛋白相同。超速离心发现这些异常脂蛋白的密度高于1.063 g/ml。