Bergstrom L V, Baker B B, Sando I
J Laryngol Otol. 1977 Sep;91(9):787-93. doi: 10.1017/s002221510008436x.
A 52-year-old man developed sudden total bilateral deafness, and unilateral facial palsy, without other symptoms and findings. He died two months later of of bronchogenic carcinoma metastatic to dura, brainstem, pons, carebellopontine angle, cerebellum and cranial nerves III, VI, VII and VIII. There was bilateral internal auditory canal erosion. Tumour replaced right facial, acoustic and vestibular nerves. Tumour infiltrated spiral ganglion, cochlear nerve, cochlear aqueduct, and destroyed nearly all facial nerve fibres to the level of the stapedius muscle. No tumour cells were found on the left, but few fibres of facial, acoustic and vestibular nerves survived. Both ears showed some cochlear outer hair cell destruction. Metastatic tumour to temporal bone or dura should be considered when loss of peripheral VIIth or VIIIth nerve function occurs.
一名52岁男性突发双侧完全性耳聋及单侧面瘫，无其他症状及体征。两个月后，他死于支气管源性癌转移至硬脑膜、脑干、脑桥、小脑脑桥角、小脑及Ⅲ、Ⅵ、Ⅶ和Ⅷ对脑神经。双侧内耳道有侵蚀。肿瘤取代了右侧面神经、听神经和前庭神经。肿瘤浸润螺旋神经节、蜗神经、蜗水管，并破坏了几乎所有至镫骨肌水平的面神经纤维。左侧未发现肿瘤细胞，但面神经、听神经和前庭神经有少量纤维存活。双耳均有一些耳蜗外毛细胞破坏。当出现外周第Ⅶ或第Ⅷ对神经功能丧失时，应考虑颞骨或硬脑膜转移性肿瘤。
