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Assignment of PTK7 encoding a receptor protein tyrosine kinase-like molecule to human chromosome 6p21.1-->p12.2 by fluorescence in situ hybridization.

作者信息

Banga S S, Ozer H L, Park S K, Lee S T

机构信息

Department of Microbiology and Molecular Genetics, UMDNJ-New Jersey Medical School, Newark 07103-2714, USA.

出版信息

Cytogenet Cell Genet. 1997;76(1-2):43-4. doi: 10.1159/000134511.

DOI:10.1159/000134511
PMID:9154124
Abstract
摘要

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Assignment of PTK7 encoding a receptor protein tyrosine kinase-like molecule to human chromosome 6p21.1-->p12.2 by fluorescence in situ hybridization.通过荧光原位杂交将编码一种受体蛋白酪氨酸激酶样分子的PTK7定位于人类染色体6p21.1→p12.2。
Cytogenet Cell Genet. 1997;76(1-2):43-4. doi: 10.1159/000134511.
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Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG.编码一种与鸡KLG密切相关的受体蛋白酪氨酸激酶样分子的人类全长PTK7 cDNA的特征分析
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Mapping of the receptor protein-tyrosine kinase 10 to human chromosome 1q21-q23 and mouse chromosome 1H1-5 by fluorescence in situ hybridization.通过荧光原位杂交将受体蛋白酪氨酸激酶10定位到人类染色体1q21 - q23和小鼠染色体1H1 - 5。
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引用本文的文献

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PTK7: an underestimated contributor to human cancer.PTK7：人类癌症中一个被低估的因素。
Front Oncol. 2024 Oct 15;14:1448695. doi: 10.3389/fonc.2024.1448695. eCollection 2024.
2
Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells.催化缺陷型受体蛋白酪氨酸激酶PTK7通过激活AP-1和NF-κB诱导基质金属蛋白酶-9，从而增强食管鳞状细胞癌细胞的侵袭表型。
Oncotarget. 2016 Nov 8;7(45):73242-73256. doi: 10.18632/oncotarget.12303.
3
PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis.
PTK7蛋白在上皮性卵巢癌中表达降低，预后较差。
Int J Clin Exp Pathol. 2014 Oct 15;7(11):7881-9. eCollection 2014.
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PTK7 as a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients, and resistance to anthracycline drugs.PTK7 作为乳腺癌患者对辅助化疗反应和蒽环类药物耐药的潜在预后和预测标志物。
Onco Targets Ther. 2014 Oct 6;7:1723-31. doi: 10.2147/OTT.S62676. eCollection 2014.
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Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma.蛋白酪氨酸激酶 7 在食管鳞状细胞癌中的致癌作用。
Cancer Sci. 2013 Aug;104(8):1120-6. doi: 10.1111/cas.12194. Epub 2013 Jun 13.