Erdinçler P, Kaynar M Y, Babuna O, Canbaz B
Instabul University, Cerrahpaşa Medical School, Department of Neurosurgery, Turkey.
Br J Neurosurg. 1997 Apr;11(2):116-20. doi: 10.1080/02688699746456.
Although hydatid disease is the most common human disease caused by helminths, cerebral and spinal involvement in hydatid disease is rare. Recurrence is common when cysts rupture during surgical removal. The authors present the results of combined treatment with surgery and mebendazole in four cerebral and five spinal cases of hydatid disease. The patients' ages ranged between 4 and 55 years with a mean of 26 years. In three of the four cranial patients who received mebendazole treatment, the cysts ruptured during surgical removal. Four of the five spinal cases had recurrent disease at the time of admission. Mebendazole was started immediately after surgery and continued over 12 months. All cases but one are stable clinically or radiologically at a mean 27 months follow-up period.
尽管包虫病是由蠕虫引起的最常见的人类疾病，但包虫病累及脑和脊髓的情况却很罕见。手术切除囊肿时囊肿破裂，复发很常见。作者介绍了4例脑包虫病和5例脊髓包虫病采用手术联合甲苯达唑治疗的结果。患者年龄在4岁至55岁之间，平均年龄为26岁。在接受甲苯达唑治疗的4例颅脑患者中，有3例在手术切除时囊肿破裂。5例脊髓病例中有4例在入院时患有复发性疾病。手术后立即开始使用甲苯达唑，并持续12个月以上。在平均27个月的随访期内，除1例病例外，所有病例在临床或影像学上均稳定。
