Selevich M I, Larin F S, Lechevich V V
Patol Fiziol Eksp Ter. 1997 Jan-Mar(1):15-7.
The effect of pyrazole (360 mg/kg, intraperitoneally) on the levels of lipid fractions was studied in the rat liver and brain. There were no differences in hepatic lipid levels after administration of pyrazole alone and in combination with ethanol (20% solution, 1 g/ kg body weight, intragastrically). Pyrazole alone or in combination with alcohol elevates the concentrations of cholesterol, total phospholipids, phosphatidylethanolamine, and cerebrosides III, reduces the levels of sphingomyelin and cardiolipin.
研究了吡唑（360毫克/千克，腹腔注射）对大鼠肝脏和大脑脂质组分水平的影响。单独给予吡唑以及吡唑与乙醇（20%溶液，1克/千克体重，灌胃）联合使用后，肝脏脂质水平没有差异。单独使用吡唑或与酒精联合使用均可提高胆固醇、总磷脂、磷脂酰乙醇胺和脑苷脂III的浓度，降低鞘磷脂和心磷脂的水平。
