Selevich M I, Karaedova L M, Ostrovskiĭ Iu M
Farmakol Toksikol. 1989 Nov-Dec;52(6):69-72.
Administration of disulfiram (200 mg/kg intragastrically for 3 days) was followed by an increase in the rat liver contents of total phospholipid fraction, triacylglycerine, lisophosphatidylcholine and a decrease in the relative level of phosphatidylethanolamine. This was associated with a decrease in the involvement of the tracer from 14C-ethanol in triacylglycerines, total phospholipids, lisophosphatidylcholine and cardiolipin. Alcohol injection (a 20% solution intraperitoneally in a dose of 1 g/kg for 30 minutes) against the background of treatment with disulfiram leads, in addition to the above-mentioned changes, to an increase of phosphatidylcholine concentration, a decrease of specific radioactivities of cholesterol, diacylglycerine and sphyngomyelin.
给予双硫仑（200毫克/千克，灌胃3天）后，大鼠肝脏中总磷脂组分、三酰甘油、溶血磷脂酰胆碱的含量增加，磷脂酰乙醇胺的相对水平降低。这与14C-乙醇示踪剂参与三酰甘油、总磷脂、溶血磷脂酰胆碱和心磷脂的过程减少有关。在双硫仑治疗的背景下注射酒精（20%溶液，腹腔注射，剂量为1克/千克，持续30分钟），除上述变化外，还会导致磷脂酰胆碱浓度增加，胆固醇、二酰甘油和鞘磷脂的比放射性降低。
