Shibahara H, Wakimoto E, Mitsuo M, Ogasawara T, Takemura T, Koyama K
Department of Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Japan.
Gynecol Oncol. 1997 May;65(2):363-5. doi: 10.1006/gyno.1997.4646.
A case of successful pregnancy after treatment of stage Ia malignant mixed Müllerian tumor of the ovary is described. This tumor is very rare and usually occurs in postmenopausal women. cis-platinum-based chemotherapy following the primary operation in the early stage is the most effective treatment, although most of the tumors have been found in the advanced stage. In this patient, treatment with unilateral salpingo-oophorectomy to preserve fertility was performed and followed by cis-platinum-based chemotherapy for 5 years. Two years after completion of the chemotherapy, she spontaneously conceived and the course of the pregnancy has been uneventful to this point.
本文描述了一例Ia期卵巢恶性混合性苗勒管肿瘤治疗后成功妊娠的病例。这种肿瘤非常罕见,通常发生在绝经后女性中。尽管大多数肿瘤在晚期才被发现,但早期原发性手术后采用顺铂为主的化疗是最有效的治疗方法。在该患者中,为保留生育功能进行了单侧输卵管卵巢切除术,随后进行了5年的顺铂为主的化疗。化疗结束两年后,她自然受孕,到目前为止妊娠过程顺利。