Leckman J F, Grice D E, Barr L C, de Vries A L, Martin C, Cohen D J, McDougle C J, Goodman W K, Rasmussen S A
Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA.
Anxiety. 1994;1(5):208-15.
Obsessive compulsive disorder (OCD) is a chronic condition characterized by an array of intrusive, upsetting thoughts and interfering, repetitive behaviors. Some forms of OCD may be etiologically related to Tourette's syndrome (TS). This cross-sectional study examines a range of obsessive compulsive (OC) symptoms which have been hypothesized to distinguish tic-related OCD from non-tic-related OCD. One hundred and seventy-seven patients with a primary DSM-IIIR diagnosis of OCD, aged 16 to 72, participated in the study. Patients with tic-related OCD (n = 56) reported more OC symptoms, including more aggressive, religious, and sexual obsessions as well as checking, counting, ordering, touching, and boarding compulsions than did patients with non-tic-related OCD (n = 121). Contrary to our expectation, these two groups of OCD patients did not differ with regard to the presence of "just right" phenomena or symptoms of psychasthenia. "Just right" phenomena and symptoms of psychasthenia, however, were both found to be associated with the current severity of OC symptoms.
强迫症(OCD)是一种慢性疾病,其特征是一系列侵入性、令人不安的想法以及干扰性的重复行为。某些形式的强迫症可能在病因上与图雷特综合征(TS)有关。这项横断面研究考察了一系列强迫观念及强迫行为(OC)症状,这些症状被认为可区分与抽动相关的强迫症和与抽动无关的强迫症。177名年龄在16至72岁之间、初步诊断为DSM-IIIR标准的强迫症患者参与了该研究。与非抽动相关强迫症患者(n = 121)相比,抽动相关强迫症患者(n = 56)报告了更多的OC症状,包括更具攻击性、宗教性和性方面的强迫观念,以及检查、计数、排序、触摸和搭乘方面的强迫行为。与我们的预期相反,这两组强迫症患者在是否存在“恰到好处”现象或神经衰弱症状方面并无差异。然而,“恰到好处”现象和神经衰弱症状均被发现与当前OC症状的严重程度相关。