Fitzgerald L S, Hanlon J T, Shelton P S, Landsman P B, Schmader K E, Pulliam C C, Williams M E
School of Pharmacy, University of North Carolina, Chapel Hill, USA.
Ann Pharmacother. 1997 May;31(5):543-8. doi: 10.1177/106002809703100503.
To evaluate the reliability of a medication appropriateness index (MAI) modified for elderly outpatients in a non-Veterans Affairs setting.
Reliability study.
General community.
Ten community-dwelling elderly (> 65 y) taking five or more regularly scheduled medications and participating in a university-based health service intervention study.
Interrater reliability of MAI ratings of 65 medications made by two clinical pharmacists for individual items and for an overall summed score was calculated by use of kappa statistics and intraclass correlation coefficient.
The interrater agreement for each of the individual MAI items was high for both appropriate and inappropriate ratings and ranged from 80% to 100% (overall kappa = 0.64). Overall agreement for the summed score was good (intraclass correlation = 0.80).
The modified MAI is a reliable instrument for evaluation of medication appropriateness in a non-Veterans Affairs, ambulatory, elderly population and may provide pharmacists with a practical and standard method to evaluate patients' drug regimens and identify some potential drug-related problems.
评估在非退伍军人事务环境中为老年门诊患者改良的用药合理性指数（MAI）的可靠性。
可靠性研究。
普通社区。
10名居住在社区的老年人（年龄>65岁），服用五种或更多常规药物，并参与一项基于大学的健康服务干预研究。
由两名临床药剂师对65种药物的MAI评分进行评估，针对各个项目以及总体总分，通过kappa统计量和组内相关系数计算评定者间信度。
对于各个MAI项目，无论是适宜还是不适宜的评分，评定者间的一致性都很高，范围在80%至100%之间（总体kappa = 0.64）。总分的总体一致性良好（组内相关系数 = 0.80）。
改良后的MAI是评估非退伍军人事务门诊老年人群用药合理性的可靠工具，可为药剂师提供一种实用且标准的方法来评估患者的药物治疗方案，并识别一些潜在的药物相关问题。
