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[来自不同种群的黄颈姬鼠(Apodemus flavicollis)核型中的独特染色体重排]

[Unique chromosome rearrangements in karyotypes of yellow-necked mice (Apodemus flavicollis) from various populations].

作者信息

Nadzhafova R S

出版信息

Genetika. 1997 Jan;33(1):126-9.

PMID:9162686
Abstract

Cytogenetic monitoring of yellow-necked mouse populations in various parts of the species range revealed deviations from the standard chromosome set in two individuals (Female from the Bryanskaya region and Male from the Samarskaya region). In both of them the wholly acrocentric chromosome set was supplemented by a large unpaired submetacentric chromosome. The C-banding showed no structural homology between these newly formed chromosomes. Obviously, they had been produced by different mechanisms, which may include amplification of paracentromeric heterochromatin in a large chromosome (Female) and classical Robertsonian fusion of two acrocentrics (Male). The low frequency and nonhomologous state of these rearrangements suggest their mutational origin.

摘要

对该物种分布范围内不同地区的黄颈姬鼠种群进行细胞遗传学监测发现,有两个个体(来自布良斯克地区的雌性和来自萨马拉地区的雄性)的染色体组偏离了标准染色体组。在这两个个体中,完全近端着丝粒染色体组都由一条大的不成对亚中着丝粒染色体进行了补充。C带分析表明,这些新形成的染色体之间不存在结构同源性。显然,它们是由不同机制产生的,可能包括一条大染色体中着丝粒旁异染色质的扩增(雌性)以及两条近端着丝粒染色体的经典罗伯逊融合(雄性)。这些重排的低频性和非同源状态表明它们起源于突变。

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