Calleri L, Porcelli A, Gallello D, Taccani C, Surico N
Cattedra di Clinica Ostetrica e Ginecologica, Facoltà di Medicina e Chirurgia--Novara, Università degli Studi, Torino.
Minerva Ginecol. 1997 Jan-Feb;49(1-2):19-23.
We tried to identify a correlation between bacterial vaginosis and PROM with the aim of proposing a future screening for pregnant women at risk for premature rupture of membranes. We made two vaginal bacteriological tests on women pregnant at 24th and 34th week, and we repeated the same test when it proved positive for infection after therapy. We did 375 tests and our study group was composed of 249 pregnant women, aged between 24 and 35. We also evaluated some variable factors as ultrasonographic gestational age redetermination, number pregnancies of oral contraceptives or IUD use, presence of risk factors presence (recurrent abortion, previous PROM, glucose metabolism alteration, immunosuppression, condylomatosis). 171 tests proved positive (total positivity percentage: 47.2%). The most common micro-organism was Ureaplasma urealyticum (49.1%) that was related to PROM in 66.7%. This result contracts with affirmations of some England authors who think that Ureaplasma hasn't an important role in PROM. This fact, if related to the other data we obtained with our study, actually current, shows a strict correlation between PROM and bacterial vaginosis, but also a different distribution of vaginal infections in our country in comparison with English countries.
我们试图确定细菌性阴道病与胎膜早破之间的相关性，目的是为有胎膜早破风险的孕妇提出未来的筛查方法。我们对妊娠24周和34周的孕妇进行了两次阴道细菌学检测，并且在治疗后感染检测结果呈阳性时重复相同检测。我们共进行了375次检测，研究组由249名年龄在24岁至35岁之间的孕妇组成。我们还评估了一些可变因素，如超声孕周重新确定、口服避孕药或宫内节育器使用次数、危险因素的存在情况（复发性流产、既往胎膜早破、糖代谢改变、免疫抑制、湿疣）。171次检测结果呈阳性（总阳性率：47.2%）。最常见的微生物是解脲脲原体（49.1%），其中66.7%与胎膜早破有关。这一结果与一些英国作者的观点相悖，他们认为解脲脲原体在胎膜早破中没有重要作用。这一事实，如果与我们目前研究获得的其他数据相关联，实际上表明胎膜早破与细菌性阴道病之间存在密切相关性，而且与英国相比，我国阴道感染的分布情况有所不同。
