Zhiburt B B, Chepel' A I, Serebrianaia N B, Mineeva N V, Ignatovich G P, Shcherbak Iu A, Ulanov N E
Ter Arkh. 1997;69(1):29-31.
Prevalence of Lewis antigens and phenotypes has been investigated in 60 healthy donors and 74 patients with ischemic heart disease. It was found that phenotype Le(a-b-) marks high risk and phenotype Le(a-b+) is a resistance marker for development of ischemic heart disease. It would be valid to elucidate relationships between Lewis system and pathogenesis of internal diseases.
在60名健康供体和74名缺血性心脏病患者中对Lewis抗原和表型的流行情况进行了调查。发现Le(a-b-)表型标志着高风险,而Le(a-b+)表型是缺血性心脏病发展的抗性标志。阐明Lewis系统与内科疾病发病机制之间的关系将是有意义的。