dos Santos F T, Pinto V M, Graeff-Teixeira C
Dept. Ciências Microbiológicas e Curso de Pós-Graduação em Biociências (Zoologia), PUCRS, Porto Alegre, RS, Brazil.
Rev Inst Med Trop Sao Paulo. 1996 May-Jun;38(3):171-5. doi: 10.1590/s0036-46651996000300002.
Wild rodents have been described as the most important hosts for Angiostrongylus costaricensis in Central America and southern Brazil. Sinantropic rodents apparently do not play a significant role as natural hosts. A search for natural infection failed to document worms in 14 mice captured in the house of a patient with diagnosis of abdominal angiostrongylosis and experimental infection of a "wild" Mus musculus strain and groups of albino swiss mice were carried out. Mortality was not significantly different and varied from 42% to 80% for Swiss mice and from 26% to 80% for "wild" mice. The high mortality of a "wild" M. musculus infected with A. costaricensis was very similar to what is observed with most laboratory mice strains. These data may be taken as indications that M. musculus is not a well adapted host for A. costaricensis, although susceptibility was apparently higher with "wild" populations of M. musculus as compared to Swiss strain.
野生啮齿动物被认为是中美洲和巴西南部哥斯达黎加血管圆线虫最重要的宿主。喜栖于人类住处的啮齿动物显然并非重要的自然宿主。在一名被诊断为腹部血管圆线虫病患者家中捕获的14只小鼠中，未发现自然感染的蠕虫，随后对“野生”小家鼠品系和白化瑞士小鼠组进行了实验性感染。瑞士小鼠的死亡率在42%至80%之间，“野生”小鼠的死亡率在26%至80%之间，两者差异不显著。感染哥斯达黎加血管圆线虫的“野生”小家鼠的高死亡率与大多数实验室小鼠品系的情况非常相似。这些数据可能表明小家鼠并非哥斯达黎加血管圆线虫的适宜宿主，尽管“野生”小家鼠种群的易感性明显高于瑞士品系。
