Colovic R B, Colovic M, Ciganovic D, Matic S, Colovic N
Institute for Digestive Diseases, Clinical Center of Serbia First Surgical Clinic Belgrade, Yugoslavia.
Hepatogastroenterology. 1997 Mar-Apr;44(14):610-2.
Leiomyosarcoma is the second most common non epithelial malignant tumor of the stomach. It is almost always a single lesion. Multiple leiomyosarcomas of the stomach are extremely rare. To our knowledge only three cases have been reported so far. We present a 40 year old female with epigastric pain, nausea, diarrhea, weight loss and melena in whom we diagnosed multiple lesions of the stomach. At operation, we found a total of 11 submucosal or subserosal lesions ranging in size from 0.5 to 6 cm in diameter localized throughout the stomach. Histological examination showed leiomyosarcoma in every lesion. Almost all the lymph nodes along curvatures had metastases. Other lymph nodes, peritoneum, liver and other organs were disease free. A total gastrectomy and Roux-en-Y esophagojejunostomy was performed. She had an uneventful recovery and has remained symptom-free so far (nine months).
平滑肌肉瘤是胃第二常见的非上皮性恶性肿瘤。它几乎总是单个病灶。胃多发平滑肌肉瘤极为罕见。据我们所知，迄今为止仅报道过3例。我们报告了一名40岁女性，有上腹部疼痛、恶心、腹泻、体重减轻和黑便症状，我们诊断其胃部有多个病灶。手术时，我们总共发现11个黏膜下或浆膜下病灶，直径从0.5厘米至6厘米不等，分布于整个胃部。组织学检查显示每个病灶均为平滑肌肉瘤。几乎所有沿胃大弯和胃小弯的淋巴结均有转移。其他淋巴结、腹膜、肝脏及其他器官均无病变。实施了全胃切除术和Roux-en-Y食管空肠吻合术。她恢复顺利，至今（9个月）仍无症状。
