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因子V缺乏与月经:一项妇科挑战。

Factor V deficiency and menstruation: a gynecologic challenge.

作者信息

Bennett K, Daley M L, Pike C

机构信息

Department of Obstetrics and Gynecology, Grace General Hospital, St. John's, Newfoundland, Canada.

出版信息

Obstet Gynecol. 1997 May;89(5 Pt 2):839-40. doi: 10.1016/s0029-7844(97)00061-6.

DOI:10.1016/s0029-7844(97)00061-6
PMID:9166342
Abstract

BACKGROUND

Menorrhagia is a well-known complication of factor V deficiency.

CASE

A 13-year-old girl with factor V deficiency presented with acute hemorrhage on day 4 of menses. Laboratory assessment revealed a hemoglobin of 36 g/L. The ultrasound appearance of a large loculated cystic mass was consistent with substantial intraperitoneal bleeding. Stabilization with blood products was followed by GnRH agonist therapy. Medical management was instituted effectively. Continued compliance with medication is essential to prevent recurrences.

CONCLUSION

Factor V deficiency is rare. Coagulation disorders of this nature pose a challenge to gynecologists involved in patient management at the time of menses.

摘要

背景

月经过多是因子V缺乏症的一种众所周知的并发症。

病例

一名13岁的因子V缺乏症女孩在月经第4天出现急性出血。实验室检查显示血红蛋白为36 g/L。超声显示一个大的分隔囊性肿块,与大量腹腔内出血相符。在用血液制品稳定病情后,采用促性腺激素释放激素激动剂治疗。药物治疗有效。持续遵医嘱服药对于预防复发至关重要。

结论

因子V缺乏症很罕见。这种性质的凝血障碍给参与月经期间患者管理的妇科医生带来了挑战。

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