Abu-Rustum N R, Curtin J P, Burt M, Jones W B
Gynecology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Obstet Gynecol. 1997 May;89(5 Pt 2):850-2. doi: 10.1016/s0029-7844(97)00033-1.
Metastatic uterine low-grade smooth-muscle tumors may present with pulmonary symptoms and radiographic lung abnormalities consistent with metastatic neoplasms. Ovarian hormone stimulation of these smooth-muscle tumors has been suggested, but the role of surgical or medical oophorectomy has not been established in patients with metastatic disease.
Two women with histologically confirmed uterine low-grade smooth-muscle tumors metastatic to the lung had progressive and complete tumor regression after oophorectomy and no further therapy.
Some uterine low-grade smooth-muscle tumors metastatic to the lung regress after oophorectomy. Removing ovarian hormone stimulation may result in complete tumor regression without the need for further therapy.
