Steffens D C, Krishnan K R
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA.
Depress Anxiety. 1996;4(6):289-93. doi: 10.1002/(SICI)1520-6394(1996)4:6<289::AID-DA5>3.0.CO;2-7.
Decision making in psychiatric diagnosis and treatment has not been evaluated systematically. The authors present a model for treatment of an acute manic episode using a decision analysis software program. Six treatment options were put into the model: lithium, valproate, carbamezepine, electroconvulsive therapy, clonazepam, and neuroleptics. Each treatment was evaluated on three factors, efficacy, tolerability, and cost, using data from the literature and pharmacy and billing information. Output from the computer program identified three top choices among the six options: valproate, carbamazepine, and lithium, with valproate emerging as the first choice using the data we inputted.
精神病诊断和治疗中的决策尚未得到系统评估。作者提出了一个使用决策分析软件程序来治疗急性躁狂发作的模型。该模型纳入了六种治疗方案：锂盐、丙戊酸盐、卡马西平、电休克疗法、氯硝西泮和抗精神病药物。利用文献数据、药房信息和计费信息，对每种治疗方案在疗效、耐受性和成本这三个因素上进行了评估。计算机程序的输出结果在这六种方案中确定了三个首选：丙戊酸盐、卡马西平和锂盐，根据我们输入的数据，丙戊酸盐成为首选。
