Minor P D
National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, UK.
Biologicals. 1997 Mar;25(1):35-40. doi: 10.1006/biol.1997.0058.
The action of live attenuated vaccines against mumps is poorly understood although their clinical efficacy is beyond doubt. The attenuated character of the vaccine is assured by consistency of production related to clinical trials, and limited studies of vaccine seeds in primates. Potency is assessed by infectivity in vitro and is subject to poorly understood sources of variation. Molecular biological studies are at an early stage.