Jamrozik Z, Królicki L, Kwieciński H, Florek M
Department of Neurology, Medical School, Warsaw, Poland.
Mater Med Pol. 1996 Jul-Sep;28(3):79-82.
In 30 patients with Parkinson's disease (PD) CT scan, isotopic cisternography and neuropsychological examination were performed to test possible relationship between cerebrospinal fluid (CSF) turnover, intellectual impairment and brain atrophy. Pathological cisternography was found in one third of the patients and it was positively correlated with the Columbia Rating Scale. Cerebral atrophy on CT was found more frequently in patients with earlier onset of PD. Combined pathological pattern on CT scan and on cisternography was correlated with intellectual decline. We conclude from this study, that in PD intellectual deterioration and brain atrophy separately are not connected with abnormal CSF turnover.
对30例帕金森病（PD）患者进行了CT扫描、同位素脑池造影和神经心理学检查，以检测脑脊液（CSF）周转率、智力损害和脑萎缩之间可能存在的关系。三分之一的患者发现有病理脑池造影表现，且与哥伦比亚评定量表呈正相关。PD发病较早的患者CT上脑萎缩更为常见。CT扫描和脑池造影的联合病理模式与智力衰退相关。我们从这项研究得出结论，在帕金森病中，智力衰退和脑萎缩单独来看均与脑脊液周转率异常无关。
