Deykin E Y, Buka S L
Department of Psychiatry, Harvard Medical School, Boston, USA.
Am J Psychiatry. 1997 Jun;154(6):752-7. doi: 10.1176/ajp.154.6.752.
This study ascertained the prevalence of posttraumatic stress disorder (PTSD) among chemically dependent adolescents and identified factors that influence the risk of PTSD after a qualifying trauma.
The study group consisted of 297 adolescents aged 15-19 years who met the DSM-III-R criteria for dependence on alcohol or other drugs and who were receiving treatment in seven publicly funded Massachusetts facilities. PTSD and other axis I diagnoses were assessed by the Diagnostic Interview Schedule. Data on risk factors were collected by a specially constructed interview schedule.
The lifetime prevalence of PTSD was 29.6% (24.3% for males and 45.3% for females), and the current prevalence was 19.2% (12.2% for males and 40.0% for females). These prevalences reflect a high occurrence of traumatic exposures and a high case rate among those who experienced trauma. The risk of PTSD varied with the nature of the trauma, the number of traumas experienced, psychiatric comorbidity, and familial characteristics. The higher rate of PTSD among females was due to a greater frequency of rape, which carries a high risk of PTSD development, and to a high rate of comorbid conditions.
The lifetime prevalence of PTSD among these chemically dependent adolescents is five times that reported for a community sample of adolescents. This extremely high rate provides new understanding of the etiologic connection between PTSD and chemical dependence and has implications for their treatment.
本研究确定了化学物质依赖青少年中创伤后应激障碍(PTSD)的患病率,并确定了影响符合条件的创伤后发生PTSD风险的因素。
研究组由297名年龄在15至19岁之间的青少年组成,他们符合DSM-III-R关于酒精或其他药物依赖的标准,且正在马萨诸塞州的七个公共资助机构接受治疗。通过诊断访谈表评估PTSD及其他轴I诊断。通过专门构建的访谈表收集危险因素的数据。
PTSD的终生患病率为29.6%(男性为24.3%,女性为45.3%),当前患病率为19.2%(男性为12.2%,女性为40.0%)。这些患病率反映了创伤暴露的高发生率以及经历创伤者中的高病例率。PTSD的风险因创伤的性质、经历的创伤数量、精神共病和家族特征而异。女性中PTSD的较高发生率是由于强奸频率较高(强奸导致PTSD发生的风险很高)以及共病率较高。
这些化学物质依赖青少年中PTSD的终生患病率是青少年社区样本报告患病率的五倍。这一极高的患病率为理解PTSD与化学物质依赖之间的病因联系提供了新的视角,并对它们的治疗具有启示意义。