Swaim L S, Maklad N F
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Medical School at Houston 77030, USA.
J Reprod Med. 1997 May;42(5):312-4.
Interstitial pregnancies are often associated with significant morbidity. The surgical treatment of such ectopic gestations often requires laparotomy and cornual resection, thus obliterating tubal and uterine continuity. Methotrexate has been shown to be 94% successful in the management of tubally implanted ectopic gestations, but few reports describe its use in interstitial pregnancies.
An 18-year-old woman who presented with an asymptomatic interstitial pregnancy was treated successfully with intramuscular methotrexate. Laparotomy and cornual resection were avoided. No adverse effects were noted.
Interstitial pregnancies can be treated successfully with intramuscular methotrexate.
间质部妊娠常伴有严重的发病率。此类异位妊娠的手术治疗通常需要剖腹手术和子宫角切除术，从而破坏输卵管和子宫的连续性。甲氨蝶呤已被证明在治疗输卵管植入的异位妊娠方面成功率为94%，但很少有报告描述其在间质部妊娠中的应用。
一名18岁无症状间质部妊娠女性经肌肉注射甲氨蝶呤成功治疗。避免了剖腹手术和子宫角切除术。未观察到不良反应。
肌肉注射甲氨蝶呤可成功治疗间质部妊娠。
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