Sanou I, Paré J, Traoré S, Modiano D, Kam K L, Kaboré J, Lamizana L, Sawadogo S A, Guiguemdé T R
Service de pédiatrie, Hopital de Ouagadougou Burkina Faso.
Sante. 1997 Jan-Feb;7(1):13-7.
During the period of transmission of malaria, from August to November of 1993 and 1994, we conducted a study to determine the frequency of the clinical forms of severe and complicated malaria. The study involved children, from 6 months through 15 years old, admitted to the pediatric ward of the hospital in Ouagadougou, Burkina Faso. The criteria for inclusion followed the definition of severe malaria stated by the World Health Organization. We carefully noted the symptoms and signs on admission. Of the total of 719 children enrolled in the study, there was a prevalence of children under 5 years old. The most frequent clinical forms were those of coma (377 cases, 52.4%), prostration (268 cases, 37.3%), convulsion (152 cases, 21.4%), anemia (115 cases, 15.9%), and hypoglycemia (55 cases, 10.3%). No renal failure form was observed. We also observed the respiratory distress form (35 cases, 4.9%) and the hemorrhagic form (11 cases, 1.5%). Malaria remains a major cause of childhood morbidity and mortality in the developing world. Early therapeutic management of febrile attacks with chloroquine would reduce the incidence of severe and complicated malaria.
在1993年和1994年8月至11月疟疾传播期间，我们开展了一项研究以确定重症和复杂型疟疾临床类型的发生频率。该研究涉及布基纳法索瓦加杜古医院儿科病房收治的6个月至15岁儿童。纳入标准遵循世界卫生组织对重症疟疾的定义。我们仔细记录了入院时的症状和体征。在该研究纳入的719名儿童中，5岁以下儿童占多数。最常见的临床类型为昏迷（377例，52.4%）、极度虚弱（268例，37.3%）、惊厥（152例，21.4%）、贫血（115例，15.9%）和低血糖（55例，10.3%）。未观察到肾衰竭类型。我们还观察到呼吸窘迫型（35例，4.9%）和出血型（11例，1.5%）。疟疾仍然是发展中世界儿童发病和死亡的主要原因。用氯喹对发热发作进行早期治疗管理将降低重症和复杂型疟疾的发病率。
