Matti P, Zardini E, Brunn E, Moghetti P, Fornalè M, Padovani E M
Clinica Pediatrica, Università degli Studi, Verona.
Minerva Ginecol. 1997 Mar;49(3):73-6.
Congenital malformations are considered the more frequent perinatal complications affecting offsprings of diabetic mothers; they represent the main cause of mortality of these neonates. Since diabetes is strictly controlled, the incidence and the seriousness of its complications are reduced from 8-10% to 2-3%. In this study we followed 56 pregnancies complicated by diabetes. There were 3 case of malformations. We correlate these with the metabolic maternal balance and with the HbA1c values. We could confirm the relationship between malformation and metabolic imbalance and also the absence of fetal malformations in women with metabolic compensation since the beginning of the pregnancy.
先天性畸形被认为是影响糖尿病母亲后代的较常见围产期并发症；它们是这些新生儿死亡的主要原因。由于糖尿病得到严格控制，其并发症的发生率和严重程度从8-10%降至2-3%。在本研究中，我们跟踪了56例并发糖尿病的妊娠。有3例畸形病例。我们将这些病例与母亲的代谢平衡以及糖化血红蛋白（HbA1c）值相关联。我们能够证实畸形与代谢失衡之间的关系，以及自妊娠开始就代谢代偿的女性中胎儿无畸形的情况。
