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[糖尿病与妊娠]

[Diabetes and pregnancy].

作者信息

Lepercq J, Timsit J

机构信息

Service de Gynécologie-Obstétrique, Hôpital Saint-Vin-cent-de-Paul, AP-HP, Université Paris V.

出版信息

Ann Med Interne (Paris). 1999 Sep;150(5):419-24.

Abstract

The presence of insulin-dependent or non insulin-dependent diabetes mellitus in pregnant women has been associated with an adverse effect on the maternal an fetal outcomes of pregnancy. The incidence of obstetrical and diabetic complications is increased, and a continuum has been observed between maternal blood glucose levels and perinatal outcome. The incidence of congenital malformations, macrosomia and prematurity is increased in offspring of diabetic mothers. Programming and intensive collaborative follow-up improve the outcome of such pregnancies. Gestational diabetes mellitus is an heterogenous condition defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. Short term complications are mainly represented by fetal macrosomia and high cesarean section rate. Women with a history of gestational diabetes mellitus are at increased risk of future diabetes, predominantly type 2. Obesity and type 2 diabetes are increased among their children.

摘要

孕妇患有胰岛素依赖型或非胰岛素依赖型糖尿病与妊娠的母体和胎儿结局的不良影响有关。产科和糖尿病并发症的发生率增加,并且在母体血糖水平和围产期结局之间观察到一种连续关系。糖尿病母亲的后代中先天性畸形、巨大儿和早产的发生率增加。规划和强化协作随访可改善此类妊娠的结局。妊娠期糖尿病是一种异质性疾病,定义为在妊娠期间出现或首次被发现的严重程度不一的碳水化合物不耐受。短期并发症主要表现为胎儿巨大和剖宫产率高。有妊娠期糖尿病病史的女性未来患糖尿病的风险增加,主要是2型糖尿病。她们的子女中肥胖和2型糖尿病的发生率也增加。

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