Bellanca G
Minerva Med. 1977 Sep 30;68(46):3229-31.
The new generation of pacemakers satisfy three basic requirements; histocompatibility, small size, and long life. Resins have been abandoned in favour of titanium cases. These are completely sealed and there is no risk of infiltration or histotoxicity. In addition, the employment of low consumption circuits and new sources of energy, especially lithium, has enabled the working life of a pacemaker to be extended virtually to its useful limits. The application of electrical stimulation to the treatment of arrhythmia has led to the creation of automatic or magnetically controlled pacemakers that come into action with pulse volleys on the appearance of otherwise intractable rhythm disturbances.
组织相容性、小尺寸和长寿命。树脂已被弃用，转而采用钛制外壳。这些外壳完全密封，不存在渗透或组织毒性风险。此外，低功耗电路和新能源尤其是锂的使用，使起搏器的使用寿命几乎延长到了其有效极限。电刺激在心律失常治疗中的应用催生了自动或磁控起搏器，这些起搏器会在出现其他难以治疗的节律紊乱并伴有脉冲群时开始工作。
