Braun U, Caplazi P, Linggi T, Graf F
Klinik für Wiederkäuer- und Pferdemedizin, Universität Zürich.
Schweiz Arch Tierheilkd. 1997;139(4):165-71.
Polycythemia associated with hepatic carcinoma was diagnosed in a 10-year-old cow, an 8-month-old heifer and a 3-year-old sheep. The cow was referred to our clinic because of weight loss, reduced appetite, hematuria, marked reddening of the mucosa of the tear canal, oral cavity and vestibule and an increased hematocrit. Clinical examination also revealed injected scleral vessels. The erythrocyte count, the PCV, hemoglobin concentration and the activities of the hepatic enzymes were increased. Ultrasonographic examination revealed a very large liver with a focal echogenic lesion. Based on all findings, a diagnosis of polycythemia associated with a liver tumor, was made. The cow was slaughtered. Multifocal liver tumors were diagnosed histologically as hepatocellular carcinoma. The heifer and sheep had similar clinical and hematological findings. Hepatocellular carcinoma was diagnosed in the heifer and cholangiocellular carcinoma in the sheep. It was concluded that in all three patients, polycythemia was caused by hepatic carcinoma.
在一头10岁母牛、一头8个月大的小母牛和一只3岁绵羊身上诊断出与肝癌相关的红细胞增多症。这头母牛因体重减轻、食欲减退、血尿、泪管、口腔和前庭黏膜明显发红以及血细胞比容升高而被转诊至我们的诊所。临床检查还发现巩膜血管充血。红细胞计数、血细胞比容、血红蛋白浓度和肝酶活性均升高。超声检查显示肝脏非常大，有一个局灶性回声病变。根据所有检查结果，诊断为与肝肿瘤相关的红细胞增多症。这头母牛被屠宰。组织学检查发现多灶性肝肿瘤为肝细胞癌。小母牛和绵羊有类似的临床和血液学表现。小母牛被诊断为肝细胞癌，绵羊被诊断为胆管细胞癌。得出的结论是，在所有这三个病例中，红细胞增多症是由肝癌引起的。
