异基因外周血干细胞初次移植治疗重型再生障碍性贫血。
Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia.
作者信息
Hsu H C, Tsai W H, Lin J S, Tzeng C H, Wang S Y, Ho C H
机构信息
Department of Medicine, Veterans General Hospital-Taipei, Taiwan, Republic of China.
出版信息
Ann Hematol. 1997 Apr;74(4):191-2. doi: 10.1007/s002770050281.
Primary allogeneic peripheral blood stem cell transplantation (allo-PBSCT) has not been previously described in the treatment of severe aplastic anemia (SAA). We report a patient with SAA who underwent primary allo-PBSCT with cells from her HLA-identical sibling and achieved rapid bone marrow reconstitution. The patient has been in complete remission with normal blood counts for 9 months following allo-PBSCT. This suggests that primary allo-PBSCT is a safe and effective alternative in the treatment of SAA.
原发性异基因外周血干细胞移植（allo - PBSCT）此前尚未见用于治疗重型再生障碍性贫血（SAA）的报道。我们报告了一名SAA患者，她接受了来自其 HLA 配型相合同胞的原发性allo - PBSCT，并实现了快速的骨髓重建。该患者在allo - PBSCT后9个月一直处于完全缓解状态，血细胞计数正常。这表明原发性allo - PBSCT是治疗SAA的一种安全有效的替代方法。
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