Chen J D, Co E, Liang J, Pan J, Sutphen J, Torres-Pinedo R B, Orr W C
Lynn Institute for Healthcare Research, Integris Baptist Medical Center, Oklahoma City, Oklahoma 73112, USA.
Am J Physiol. 1997 May;272(5 Pt 1):G1022-7. doi: 10.1152/ajpgi.1997.272.5.G1022.
The aim of this study was to investigate the developmental change of gastric myoelectrical activity in humans. Five groups of healthy subjects were studied, including 10 preterm newborns, 8 full-term newborns, 8 full-term infants (ages 2-6 mo), 9 children (ages 4-11 yr), and 9 adults. Gastric myoelectrical activity was recorded using surface electrogastrography for 30 min before and 30 min after a test meal in each subject. Spectral analysis methods were applied to compute the parameters of the electrogastrogram (EGG). The results showed that the percentage of 2- to-4-cycles/min (cpm) slow waves was 26.6 +/- 3.9% in the preterm newborns, 30.0 +/- 4.0% in full-term newborns, 70 +/- 6.1% in 2- to 6-mo-old infants (P < 0.001 compared with newborns), 84.6 +/- 3.2% in 4- to 11-yr-old children (P < 0.03 compared with infants), and 88.9 +/- 2.2% in the adults (P > 0.05 compared with children). In conclusion, gastric slow waves are absent at birth, and there is a maturing process after birth. Age-matched controls are necessary for the interpretation of EGG data from neonates and infants, whereas EGG data in children are the same as in adults.
本研究的目的是调查人类胃肌电活动的发育变化。对五组健康受试者进行了研究，包括10名早产新生儿、8名足月新生儿、8名足月婴儿（2 - 6个月龄）、9名儿童（4 - 11岁）和9名成年人。在每位受试者进食试验餐之前和之后30分钟，使用表面胃电图记录胃肌电活动。应用频谱分析方法计算胃电图（EGG）的参数。结果显示，每分钟2至4次周期（cpm）慢波的百分比在早产新生儿中为26.6±3.9%，足月新生儿中为30.0±4.0%，2至6个月龄婴儿中为70±6.1%（与新生儿相比，P<0.001），4至11岁儿童中为84.6±3.2%（与婴儿相比，P<0.03），成年人中为88.9±2.2%（与儿童相比，P>0.05）。总之，出生时胃慢波不存在，出生后有一个成熟过程。在解释新生儿和婴儿的EGG数据时，年龄匹配的对照是必要的，而儿童的EGG数据与成年人相同。
