Salzman M B, Rubin L G
University of California, Los Angeles School of Medicine, USA.
Nutrition. 1997 Apr;13(4 Suppl):15S-17S. doi: 10.1016/s0899-9007(97)00217-7.
Microorganisms causing vascular catheter-related sepsis gain access to the bloodstream through either the skin at the catheter insertion site or through the catheter hub. The catheter insertion site is probably the predominant portal for microorganisms in catheters in place for a short time, but the catheter hub may play an increasingly important role in infection in association with long-term catheters, particularly those that are subcutaneously tunneled. Although transient contamination of the catheter hub does not cause infection, certain microorganisms may migrate endoluminally and enter the bloodstream, causing bacteremia or fungemia.
引起血管导管相关败血症的微生物可通过导管插入部位的皮肤或导管接头进入血液循环。对于短期留置的导管，导管插入部位可能是微生物进入的主要途径，但对于长期导管，尤其是皮下隧道式导管，导管接头在感染中可能发挥越来越重要的作用。尽管导管接头的短暂污染不会导致感染，但某些微生物可能会沿管腔内迁移并进入血液循环，引起菌血症或真菌血症。
