Guilleminault C, Hill M H, Simmons F B, Powell N, Riley R, Stoohs R
Stanford University Sleep Disorders Clinic and Research Center, Palo Alto CA 94304, USA.
Respir Physiol. 1997 Apr;108(1):11-22. doi: 10.1016/s0034-5687(97)02529-2.
We studied five adult male patients with central sleep apnea syndrome (> 75% of the monitored events being central) during sleep using a fiberoptic scope and EMG monitoring of the superior and middle constrictors of the pharynx and the genioglossus and geniohyoid muscles. The fiberoptic investigation revealed a spontaneous decrease in the size of the airway during central apneas, without negative intrathoracic pressure or activation of the superior and middle pharyngeal constrictor muscles. We found a mean maximum decrease of 71 +/- 7% in the cross-sectional area of the airway and an absence of superior-middle pharyngeal constrictor EMG discharge. We did not observe any complete collapses of the airway.
我们使用纤维喉镜以及对咽部上、中缩肌和颏舌肌、颏舌骨肌进行肌电图监测,对5名患有中枢性睡眠呼吸暂停综合征(监测到的事件中超过75%为中枢性)的成年男性患者进行了睡眠期间的研究。纤维喉镜检查显示,在中枢性呼吸暂停期间气道尺寸自发减小,没有胸腔内负压,也没有咽部上、中缩肌的激活。我们发现气道横截面积平均最大减小71±7%,且上-中咽部缩肌肌电图无放电。我们未观察到气道有任何完全塌陷的情况。